Breathing can be affected by the pH level of the blood. Chemoreceptors send signals to the medulla and this determines the depth and rate of breathing. At low pH levels the medulla becomes stimulated and this results in an increase in breathing rate. When pH levels are high there is a decrease in breathing rate due to a lack of stimulation.
Most of the time breathing is automatic, however other parts of the brain can override the medulla and pons to make breathing a conscious effort, such as when swimmers hold their breath or when breathing is controlled while meditating.
References:
http://people.hofstra.edu/sina_y_rabbany/engg81/breathingcoordination.html
www.cdli.ca/~dpower/resp/control.htm
Read Human nervous system here
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